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Gavin King

Assistant Professor
College of Arts & Science
Physics
573-882-3217
kinggm@missouri.edu

Areas of Expertise

Biography

Individual biological molecules can be directly interrogated by techniques such as atomic force microscopy (AFM). In contrast, bulk methods yield ensemble averages that can obscure asynchronous activities. Further, traditional structural characterization techniques are notoriously difficult to apply to membrane proteins. However, these ubiquitous and pharmaceutically significant molecules are well suited to high-resolution AFM investigations. We are developing and implementing unique high-precision single molecule techniques to shed light on the structure, structural energetics, and conformational dynamics of biomolecules including membrane proteins.

An ultrastable atomic force microscope complements traditional molecular characterization techniques by providing an atomically precise means to address this question in physiologically relevant conditions.

 

May be contacted directly by media: No

 

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